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Tuesday, November 20, 2012

Conventional Treatments For Mesothelioma


Despite the continuing research and studies in the field of mesothelioma cancer is difficult to treat. This attack is rare but aggressive about 2,500 people in the U.S. each year. Conventional treatments for mesothelioma are surgery, chemotherapy and radiotherapy.


Surgery


Surgery in patients with pleural mesothelioma and peritoneal dialysis therefore be used. Surgeons prefer surgery when the tumor is located and is practically tumor debulking. Today many of the specialists of hot mesothelioma chemotherapy in combination with surgery. In the method of the current heated chemotherapy may be used in the surgical cavity for all macro-and micro-metastases which the surgeon may excise bath. Thus, the cytotoxic effects of chemotherapy can be administered directly to the tissues, where it is needed.There are several types of surgery, including surgery of lung extrapleural pneumonectomy and Combat (EPP). In combat lung surgery, surgeons remove the lining of the lungs and mesothelioma patients all visible tumor, but spares the lung. Extrapleural pneumonectomy (EPP) is a radical surgical procedure involves removal of the diseased lung, part of the pericardium (membrane covering the heart), part of the diaphragm (muscle between the lungs and the abdomen), and part of the parietal pleura ( lining of the breast). DPI is a complex and invasive.


Chemotherapy


Chemotherapy is called systemic therapy, including cytotoxic drugs (cell-killing) oral and intravenous to kill cancer cells. These drugs kill both cancerous and healthy. Some chemotherapy agents commonly used to treat mesothelioma are cisplatin and pemetrexed. Actually, cisplatin and pemetrexed (Alimta mark) in combination, the only FDA approved chemotherapy for mesothelioma.


Radiation


Radiation can be an important part of the treatment of mesothelioma and can be delivered by various methods. But if the cancer affects the lungs and around the heart can be difficult for doctors the right amount for the intensive care unit in order to shrink the tumor without morbidity provide disposal is necessary. A new option, radiation therapy, IMRT, or intensity modulated can affect cancer cells more precisely and prevent healthy cells. When performed by experienced physicians, we can expect better results with fewer side effects.


Besides these methods, there are today many clinical studies, the. For new approaches for mesothelioma These include various biological response modifiers, such as anti-angiogenesis. Decades ago, Dr. Judah Folkman discovered that tumors of a growing network of blood vessels needed to continue its growth.Blood vessels carry oxygen and nutrients to the tumor cells and tumor vessels without what would have to be removed to continue its growth. Folkman hypothesized that the ability of tumor cells to cut new blood supply (angiogenesis) to generate an effective and probably less toxic to cancer treatment.


During the last decade, universities and biotechnology companies have been working hard for the synthesis of the identification and management of anti-angiogenesis drugs - medicines stop angiogenesis new blood vessels. There has been some success in several types of cancer, including mesothelioma. Anti-angiogenesis drugs in mesothelioma are bevacizumab media, and other tyrosine kinase. Today, researchers are still trying to make this effective method mesothelioma, but admitted it was the clinical use of angiogenesis inhibitors difficult than expected.

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